Re: MKULTRA connection...
Wikipedia has some good info on MKULTRA
Here is the relevant portion:
Central Intelligence Agency documents suggest that the agency considered and explored uses of radiation for the purpose of mind control as part of MKULTRA. Other early efforts focused on LSD, which appears to have formed the majority of research as time went on. Experiments included administering the drug to CIA employees, military personnel, doctors, other government agents, prostitutes, mentally ill patients, and members of the general public in order to study their reactions, usually without the subject's knowledge.
The experiments often took a sadistic turn. Gottlieb was known to torture victims by locking them in sensory deprivation chambers while under the psychedelic influence of LSD, or to make recordings of psychiatric patients' therapy sessions, and then play a tape loop of the patient's most self-degrading statement over and over through headphones after the patient had been restrained in a straitjacket and dosed with LSD. Gottlieb himself took LSD frequently, locking himself in his office and taking copious notes.
Efforts to "recruit" subjects were often illegal even discounting the fact that drugs were being administered (though actual use of LSD, for example, was legal in the United States until 1967). In Operation Midnight Climax, the CIA set up several brothels to obtain a selection of men who would be too embarrassed to talk about the events. The brothels were equipped with one-way mirrors and the "sessions" were taped for later viewing.
Some subjects' participation was consensual, and in these cases, the subjects appeared to be singled out for even more horrific experiments. In one case, a selection of volunteers were given LSD for 69 days straight.
LSD was eventually dismissed by the researchers as too unpredictable in its effects. Although useful information was sometimes obtained through questioning subjects on LSD, not uncommonly the most marked effect would be the subject's absolute and utter certainty that they were able to withstand any form of interrogation attempt, even physical torture.
Another technique was connecting a barbiturate IV into one arm and an amphetamine IV into the other. The barbiturates were released into the subject first, and as soon as the subject began to fall asleep, the amphetamines were released. The subject would begin babbling incoherently at this point, and it was sometimes possible to ask questions and get useful answers. This treatment was discarded as it often resulted in the death of the patient from physical side effects of the drug combination, thus making further interrogation impossible. Other experiments involved heroin, mescaline, psilocybin, scopolamine, marijuana, alcohol, and sodium pentothal.
There is no evidence that the CIA (or anyone else) has actually succeeded in controlling a person's actions through the "mind control" techniques that are known to have been attempted in the MKULTRA projects. The file destruction undertaken at the order of CIA Director Richard Helms in 1972 makes a full investigation of claims impossible.
A secretive arrangement granted a percentage of the CIA budget. The MKULTRA director was granted 6% of the CIA operating budget in 1953, without oversight or accounting.
 Canadian experiments
The experiments were even exported to Canada when the CIA recruited Albany, New York doctor D. Ewen Cameron, author of the psychic driving concept which the CIA found particularly interesting. In it he described his theory on correcting madness, which consisted of erasing existing memories and rebuilding the psyche completely. He commuted to Montreal every week to work at the Allan Memorial Institute and was paid $69,000 from 1957 to 1964 to carry out MKULTRA experiments there. The CIA appears to have given him the potentially deadly experiments to carry out since they would be used on non-U.S. citizens.
In addition to LSD, Cameron also experimented with various paralytic drugs as well as electroconvulsive therapy at 30 to 40 times the normal power. His "driving" experiments consisted of putting subjects into drug-induced coma for weeks at a time (up to three months in one case) while playing tape loops of noise or simple repetitive statements. His experiments were typically carried out on patients who had entered the institute for minor problems such as anxiety disorders and postpartum depression, many of whom suffered permanently from his actions.
It was during this era that Cameron became known worldwide as the first chairman of the World Psychiatric Association as well as president of the American and Canadian psychiatric associations. Cameron had also been a member of the Nuremberg medical tribunal only a decade earlier.
In December 1974, The New York Times reported that the CIA had conducted illegal domestic activities, including experiments on U.S. citizens, during the 1960s. That report prompted investigations by both the U.S. Congress (in the form of the Church Committee) and a presidential commission (known as the Rockefeller Commission) into the domestic activities of the CIA, the FBI, and intelligence-related agencies of the military.
In the summer of 1975, congressional hearings and the Rockefeller Commission report revealed to the public for the first time that the CIA and the Department of Defense had conducted experiments on both cognizant and unwitting human subjects as part of an extensive program to influence and control human behavior through the use of psychoactive drugs such as LSD and mescaline and other chemical, biological, and psychological means. They also revealed that at least one subject had died after administration of LSD.
Frank Olson, a United States Army biochemist and biological weapons researcher, was given LSD without his knowledge or consent in 1953 as part of a CIA experiment, and allegedly committed suicide a week later following a severe psychotic episode. A CIA doctor assigned to monitor Olson's recovery was supposedly asleep in another bed in a New York City hotel room when Olson jumped through the window to fall ten stories to his death.
Olson's son disputes this version of events, and maintains that his father was murdered due to his knowledge of the sometimes-lethal interrogation techniques employed by the CIA in Europe, used on Cold War prisoners. Frank Olson's body was exhumed in 1994, and cranial injuries suggested Olson had been knocked unconscious before exiting the window.
The CIA's own internal investigation, by contrast, claimed Gottlieb had conducted the experiment with Olson's prior knowledge, although neither Olson nor the other men taking part in the experiment were informed the exact nature of the drug until some 20 minutes after its ingestion. The report further suggested that Gottlieb was nonetheless due a reprimand, as he had failed to take into account suicidal tendencies Olson had been diagnosed as suffering from which might well have been exacerbated by the LSD.
Subsequent reports would show that another person, Harold Blauer, a professional tennis player in New York City, died as a result of a secret Army experiment involving mescaline.
The congressional committee investigating the CIA research, chaired by Senator Frank Church, concluded that "[p]rior consent was obviously not obtained from any of the subjects". The committee noted that the "experiments sponsored by these researchers . . . call into question the decision by the agencies not to fix guidelines for experiments." (Documents show that the CIA participated in at least two of the DOD committees whose discussions, in 1952, led up to the issuance of the memorandum by Secretary of Defense Wilson which initiated the project.)
Following the recommendations of the Church Committee, President Gerald Ford in 1976 issued the first Executive Order on Intelligence Activities which, among other things, prohibited "experimentation with drugs on human subjects, except with the informed consent, in writing and witnessed by a disinterested party, of each such human subject" and in accordance with the guidelines issued by the National Commission. Subsequent orders by Presidents Carter and Reagan expanded the directive to apply to any human experimentation.
Following on the heels of the revelations about CIA experiments were similar stories about the Army. In response, in 1975 the Secretary of the Army instructed the Army Inspector General to conduct an investigation. Among the findings of the Inspector General was the existence of the then-still-classified 1953 Wilson memorandum.
In response to the Inspector General's investigation, the Wilson Memorandum was declassified in August 1975. The Inspector General also found that the requirements of the 1953 memorandum had, at least in regard to Army drug testing, been essentially followed as written. The Army used only "volunteers" for its drug-testing program, with one or two exceptions. However, the Inspector General concluded that the "volunteers were not fully informed, as required, prior to their participation; and the methods of procuring their services, in many cases, appeared not to have been in accord with the intent of Department of the Army policies governing use of volunteers in research." The Inspector General also noted that "the evidence clearly reflected that every possible medical consideration was observed by the professional investigators at the Medical Research Laboratories." This conclusion, if accurate, is in striking contrast to what took place at the CIA.
In Canada, the issue took much longer to surface, becoming widely known in 1984 on a CBC news show, The Fifth Estate. It was learned that not only had the CIA funded Dr. Cameron's efforts, but perhaps even more shockingly, the Canadian government was fully aware of this, and had later provided another $500,000 in funding to continue the experiments. This revelation largely derailed efforts by the victims to sue the CIA as their U.S. counterparts had, and the Canadian government eventually settled out of court for $100,000 to each of the 127 victims.